Scientific Instruments Nijmegen

Categories - GI- Electron microscopy

  Plunge freezer
Short namePlunge freezer
Full nameHG 001 Plunger injection device

With this plunger (present in the fume hood in room HG01.216) small pieces of material (e.g. cells on a membrane) can be injected extremely rapidly in cold liquid propane sothat damage due to the formation of water crystals is limited. Cryo-fixation is yet an exhausive method, but the great advantage is that this approach induces in general less artifacts than chemical fixation. The next step in TEM preparation is freeze-substitution (see B).

CategoryGI- Electron microscopy
LocationHG 01.216
Contact 1Geert-Jan Janssen
Room: Huygens 01.222
Contact 2Liesbeth Pierson
Room: HG01.222